From July 1 to July 5 of 1938, nearly 2,000 Civil War veterans—including around 25 from the battle itself--descended on Gettysburg, Pennsylvania for the 75th anniversary of the battle, this time ...

Let's not forget that Sporty Spice Melanie C went on the record to deny she'd ever take part in a reunion as little as two months before the group's last big touring comeback in 2022.

سبتمبر هو محطة نتوقف عندها لنحي الذكرى وكذلك نتزود منها بوقود ألايمان ونقوم بمراجعت الذات عبر اعادة قراة لسرديات التاريخ وننطلق نحو المستقبل.

Welcome to the Scle Family page at Surname Finder, a service of Genealogy Today. Our editors have compiled this checklist of genealogical resources, combining links to commercial databases along with user-contributed information and web sites for the Scle surname. As additional sources for vital records, original documents, vintage photographs ...

JAMA Dermatol. 2022; 149 (9):1071-5 (ISSN: 2168-6084) IMPORTANCE: Several chemotherapeutic agents have been reported to induce subacute cutaneous lupus erythematosus (SCLE). To our knowledge, this is the first report to date of SCLE induced by monotherapeutic gemcitabine hydrochloride and includes a comprehensive review of all published cases ...

نفّذت هيئة الطرق والمواصلات في دبي، بالتعاون مع بلدية دبي، حملة تفتيشية حول 27 محطة من محطات مترو دبي لرصد وقوف

Subacute Cutaneous Lupus Erythematosus (SCLE) is a particular form of lupus that affects the skin, causing red, itchy rashes. This particular type of lupus can have 2 common manifestations: "One type begins with red, pimple-like bumps on the skin and can develop into red, scaly lesions that resemble psoriasis," says Dr. Kellie Reed ...

Subacute cutaneous lupus erythematosus (SCLE) is a clinically distinct subset of lupus erythematosus that is most often present in white women aged 15 to 40. Lupus erythematosus may manifest itself as systemic disease or in a purely cutaneous form also known as incomplete lupus erythematosus with non-scarring, non-indurated, photosensitive, non ...

Mining expected to begin before 2022. Mine has an average life of 20 years and 350,000 tonnes of manganese to be shipped yearly. Neighbouring communities will benefit. Construction and upgrading of roads, wharf and power generation facilities. Employment for approximately 1,200 persons during the peak of construction and 300 - 400 during ...

Subset of lupus erythematosus intermediate between discoid lupus erythematosus and systemic lupus erythematosus. It is characterized by papulosquamous discoid plaques or annular polycyclic lesions occurring mainly around the neck, on the back and front of the trunk and on the outer aspects of the arms. They usually heal without scarring. Photosensitivity, diffuse non-scarring alopecia and ...

Hypopigmentation in subacute cutaneous lupus erythematosus (SCLE). Permanent vitiligo-like depigmentation in the face of a patient with SCLE (Callen and Klein 1988, David et al. 1984, Molad et al. 1987, Shou-yi et al. 1987, Sontheimer 1985a, Sontheimer et al. 1979). These lesions can predate the onset of SCLE lesions; however, DLE lesions are ...

This activity will discuss subacute cutaneous lupus erythematosus (SCLE). SCLE is a subtype of CLE presenting as symmetric, non-scarring photosensitive erythematous rash usually over syn-exposed areas like face, neck, arms, upper back, and shoulders. Etiology. There is no well-defined etiology for systemic lupus erythematosus.

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Subacute cutaneous lupus due to protein pump inhibitors (PPI-induced SCLE) is more likely to affect the legs than SCLE that occurs on its own (primary SCLE) It took from 3 weeks to 12 years after starting the PPI before SCLE occurred (median time was 8 months) It took 1 week to 5 months for the SCLE to resolve after stopping the PPI. Increased ...

The initial appearance of subacute cutaneous lupus erythematosus (SCLE) skin lesions in conjunction with Ro/SS-A autoantibodies occurring as an adverse reaction to hydrochlorothiazide [ drug ...

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The SCLE subtype of cutaneous lupus erythematosus is an autoimmune disease that primarily affects the skin (2). Up to 50% of the SCLE patients manifest criteria for systemic LE (SLE) but with a mild systemic disease evolution (3). The SCLE patients manifesting SLE features show a lower incidence of renal disease, and the central nervous system ...

Background Subacute cutaneous lupus erythematosus (SCLE) lacks consensus diagnostic criteria and the pathogenesis is poorly understood. There are increasing reports of SCLE induced by monoclonal antibodies (mAbs), but there are limited data on the aetiology, clinical characteristics and natural course of this disease. Methods We devised a set of diagnostic criteria for SCLE in collaboration ...

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Subacute cutaneous lupus erythematosus (SCLE) is a distinct entity with specific clinical and serologic features that was first described by Gilliam in 1977 (Gilliam, 1977), with expanded discussion in 1979 (Sontheimer et al., 1979) and 1982 (Gilliam and Sontheimer, 1982). Most patients with SCLE are sensitive to sunlight and have prominent cutaneous and musculoskeletal complaints but ...

There were 64 SCLE patients: 36 with PPI-induced SCLE and 28 patients with primary SCLE. Results: Twenty-six patients (72%) had pre-existing SLE in the PPI-induced SCLE group. Lower limb skin lesions were significantly more prevalent in the PPI group (p < ). The prevalence of anti-Ro and anti-Ro-52 antibodies was numerically higher in the ...

We report here 5 additional cases of subacute cutaneous lupus erythematosus (SCLE) induced or exacerbated by PPIs, with a detailed summary of 2 cases. CASE REPORTS. Case 1. A 63-year-old woman with Addison's disease had been substituted with per-oral hydrocortisone, 25 mg daily, for 41 years. Fourteen years earlier she had an attack of SCLE ...

Drug-induced lupus is a well-characterized phenomenon, classically associated with anti-histone antibodies; management involves removing the offending agent. SCLE can be associated with medications, most commonly calcium channel blocker therapy [1]. Drug-induced DM is less well characterized but can occur in the setting of a variety of ...

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Background: It has been over three decades sincethe first report of drug-induced subacute cutaneouslupus erythematosus (DI-SCLE) was described. Withan increasing variety of implicated drugs and thepotential for publication bias, we must consider: 1) hasthere been a change in drugs most often reported inDI-SCLE over time, and, 2) if so, of which drugs shouldclinicians be most suspicious in the ...

Drug-induced subacute cutaneous lupus erythematosus is an uncommon disorder associated with the use of pharmacological agents including systemic chemotherapy. We report a case of docetaxel-induced subacute cutaneous lupus erythematosus in a 60-year-old Caucasian with Sjögren's syndrome diagnosed 2 months after receiving docetaxel as part of the adjuvant FEC-D (5-fluorouracil ...

Drug-induced subacute cutaneous lupus erythematosus (DI-SCLE) is subacute cutaneous lupus erythematosus (SCLE) in which the disease onset is associated with the ingestion of an offending medication. It is estimated that approximately one-third of all SCLE cases are Idiopathic SCLE and DI-SCLE are serologically, histopathologically, and clinically identical, with both ...

Reunion. DAVID MAMET 1976. AUTHOR BIOGRAPHY. PLOT SUMMARY. CHARACTERS. THEMES. STYLE. HISTORICAL CONTEXT. CRITICAL OVERVIEW. CRITICISM. SOURCES. FURTHER READING. David Mamet is one of the most celebrated American playwrights of the twentieth century. Mamet, who has won numerous prestigious awards for his plays, is best known for his use of dialogue that captures the rhythms and idiom of ...

Subacute cutaneous lupus erythematosus (SCLE) is a clinically distinct disease that is associated with systemic lupus erythematosus in 50% of patients, and can be associated with Sjögren's syndrome and patients with a deficiency in the second and fourth components of complement. SCLE presents as a small, erythematous, scaly papular eruption in a photosensitive distribution that subsequently ...

Strongly associated with systemic findings. Inflammatory infiltrate seen in the superficial dermis on biopsy. Subacute cutaneous lupus erythematosus (SCLE) Photosensitive cutaneous eruption lasting longer than ACLE but without scarring. 10%-15% of patients go on to have systemic findings. Inflammatory infiltrate seen in the upper dermis on biopsy.

We report on a 54‐yr‐old who developed subacute cutaneous lupus erythematosus (SCLE) during treatment with etanercept. A 54‐yr‐old woman received etanercept 25 mg subcutaneously twice a week since 7 September 1999 for the treatment of active seropositive nodular rheumatoid arthritis. Other medications included methotrexate 15 mg ...

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SCLE can occur anywhere on your body except your face, and like other types of cutaneous lupus, is often triggered by sunlight. Certain prescription drugs can also cause SCLE, especially some heart medications, proton pump inhibitors, anti-fungals, chemotherapy medications and tumor necrosis factor blockers. In one of the largest case studies ...

Proton pump inhibitors (PPIs) are associated with very infrequent cases of subacute cutaneous lupus erythematosus (SCLE), a non-scarring dermatosis that can develop in sun-exposed areas.

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